TitleZebrafish: A Marvel of High-Throughput Biology for 21st Century Toxicology
Publication TypeJournal Article
Year of Publication2014
AuthorsBugel, SM, Tanguay, RL, Planchart, A
JournalCurrent Environmental Health Reports
Volume1
Issue4
Start Page341
Type of Article09/2014
Abstract

The evolutionary conservation of genomic, biochemical, and developmental features between zebrafish and humans is gradually coming into focus, with the end result that the zebrafish embryo model has emerged as a powerful tool for uncovering the effects of environmental exposures on a multitude of biological processes with direct relevance to human health. In this review, we highlight advances in automation, high-throughput screening, and analysis that leverage the power of the zebrafish embryo model for unparalleled advances in our understanding of how chemicals in our environment affect our health and wellbeing.