Robyn Tanguay

Center Director

Project Leader

Dr. Robyn Leigh Tanguay is an internationally recognized scholar whose work on zebrafish models has advanced the world’s understanding of how chemicals impact the biological development of humans. In 2011, she was named an Oregon State University Distinguished Professor, the university’s highest honor. And she is invited regularly to speak to regulators and private companies about biosafety in commercial development.

Associated Research

Predicting Toxicity of PAH Mixtures

External Profile

Sinnhuber Aquatic Research Laboratory

Recent Superfund Publications

2025

Mary LS, Mcclure RS, Truong L, Carrell SJ, Waters KM, Tanguay RL Phenotypically anchored transcriptomics across diverse agrichemicals reveals conserved pathways and unique gene expression signatures in zebrafish Front Toxicol 2025 PubMed PMC12575134

Morshead ML, Truong L, Carrell SJ, Scott RP, Anderson KA, Tanguay RL Chemical structure drives developmental toxicity of alkyl-substituted naphthalenes in zebrafish Environment International 2025 PubMed PMC12560828

Degnan DJ, Bramer LM, Truong L, Tanguay RL, Gosline SJ, Waters KM bmdrc: Python package for quantifying phenotypes from chemical exposures with benchmark dose modeling PLoS Comput Biol 2025 PubMed PMC12313058

Rude CI, Smith JN, Scott RP, Schultz KJ, Anderson KA, Tanguay RL A mixture parameterized biologically based dosimetry model to predict body burdens of polycyclic aromatic hydrocarbons in developmental zebrafish toxicity assays. Toxicol Sci 2025 PubMed PMC12118961

Morshead ML, Tanguay RL Advancements in the Developmental Zebrafish Model for Predictive Human Toxicology. Curr Opin Toxicol 2025 PubMed PMC11780918

Perone DM, Annalora AJ, Goldstone JV, Dickey AN, Salanga MC, Francolini RD, Wright FA, Marcus CB, Tanguay RL, Garcia-jaramillo M Zebrafish Cyp1b1 knockout alters eye and brain metabolomic profiles, affecting ocular and neurobehavioral function. Toxicol Appl Pharmacol 2025 PubMed PMC12083501

Morshead ML, Truong L, Simonich MT, Moran JE, Anderson KA, Tanguay RL Developmental toxicity of alkylated PAHs and substituted phenanthrenes: Structural nuances drive diverse toxicity and AHR activation. Chemosphere 2025 PubMed PMC11732715

2024

Rude CI, Wilson LB, Ladu JK, Lalli PM, Colby SM, Schultz KJ, Smith JN, Waters KM, Tanguay RL Aryl hydrocarbon receptor-dependent toxicity by retene requires metabolic competence. Toxicol Sci 2024 PubMed PMC11514837

Rericha Y, Mary LS, Truong L, Mcclure RS, Martin JK, Leonard SW, Thunga P, Simonich MT, Waters KM, Field JA, Tanguay RL Diverse PFAS produce unique transcriptomic changes linked to developmental toxicity in zebrafish. Front Toxicol 2024 PubMed PMC11298493

Stagaman K, Alexiev A, Sieler MJ, Hammer A, Kasschau KD, Truong L, Tanguay RL, Sharpton TJ The zebrafish gut microbiome influences benzo[a]pyrene developmental neurobehavioral toxicity. Sci Rep 2024 PubMed PMC11199668