Title | Dietary and inhalation exposure to polycyclic aromatic hydrocarbons and urinary excretion of monohydroxy metabolites--a controlled case study in Beijing, China. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Zhang, Y, Ding, J, Shen, G, Zhong, J, Wang, C, Wei, S, Chen, C, Chen, Y, Lu, Y, Shen, H, Li, W, Huang, Y, Chen, H, Su, S, Lin, N, Wang, X, Liu, W, Tao, S |
Journal | Environ Pollut |
Volume | 184 |
Pagination | 515-22 |
Date Published | 2014 Jan |
ISSN | 1873-6424 |
Keywords | Adult, Biological Markers, China, Diet, Environmental Exposure, Female, Food Contamination, Humans, Inhalation Exposure, Male, Polycyclic Hydrocarbons, Aromatic, Young Adult |
Abstract | Daily dietary and inhalation exposures to 16 parent polycyclic aromatic hydrocarbons (PAHs) and urinary excretion of 13 monohydroxy metabolites (OHPAHs) were monitored for 12 non-smoking university students in Beijing, China, during a controlled feeding experiment. The relationship between the urinary excretion of OHPAHs and the uptake of PAHs was investigated. The results suggest severe exposure of the subjects to PAHs via both dietary and inhalation pathways. Large increase of most urinary OHPAHs occurred after the ingestion of lamb kabob. Higher concentrations of OHPAHs were observed for female subjects, with the intakes of parent PAHs lower than those by males, likely due to the gender differences in metabolism. It appears that besides 1-PYR, metabolites of PHE could also be used as biomarkers to indicate the short-term dietary exposure to PAHs and urinary 3-BaA may serve as the biomarker for inhalation intake of high molecular weight PAHs.
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DOI | 10.1016/j.envpol.2013.10.005 |
Alternate Journal | Environ. Pollut. |
PubMed ID | 24177434 |
PubMed Central ID | PMC4299857 |
Grant List | P42 ES016465 / ES / NIEHS NIH HHS / United States |