TitleIdentification and Toxicological Evaluation of Unsubstituted PAHs and Novel PAH Derivatives in Pavement Sealcoat Products.
Publication TypeJournal Article
Year of Publication2016
AuthorsTitaley, IA, Chlebowski, A, Truong, L, Tanguay, RL, Simonich, SLMassey
JournalEnviron Sci Technol Lett
Volume3
Issue6
Pagination234-242
Date Published2016
ISSN2328-8930
Abstract

Pavement sealcoat products contain high concentrations of unsubstituted polycyclic aromatic hydrocarbons (PAHs), but the assessment of the potential toxicological impact is limited without the inclusion of PAH derivatives. This study determined the concentrations of 23 unsubstituted PAHs, 11 high molecular weight-PAHs (MW302-PAHs), and 56 PAH derivatives, including 10 methyl-PAHs (MPAHs), 10 heterocyclic-PAHs (Hetero-PAHs), 26 nitrated-PAHs (NPAHs), and 10 oxygenated-PAHs (OPAHs) in coal-tar and asphalt based sealcoat products and time point scrapes. Inclusion of MW302-PAHs resulted in an increase of 4.1-38.7% in calculated benzo[]pyrene-carcinogenic equivalent (B[]P) concentrations for the coal-tar based products. Increases in some NPAH and OPAH concentrations were measured after application, suggesting the possibility of photochemical transformation of unsubstituted PAHs. The Ames assay indicated that the asphalt based product was not mutagenic, but the coal-tar based sealcoat products were. The zebrafish developmental toxicity tests suggested that fractions where NPAHs and OPAHs eluted have the most significant adverse effects.

Alternate JournalEnviron Sci Technol Lett
PubMed ID30079367
PubMed Central IDPMC6075666
Grant ListP30 ES000210 / ES / NIEHS NIH HHS / United States
P42 ES016465 / ES / NIEHS NIH HHS / United States