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PAH Fate and Exposure
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PAH Fate and Exposure
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PAH Health Outcomes
Mechanisms of PAH Susceptibility
PAH Remediation and Transformations
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Katrina M Waters
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A
Goodale BC
,
La Du JK
,
Bisson WH
,
Janszen DB
,
Waters KM
,
Tanguay RL
.
AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish.
PLoS One. 2012 ;7(1):e29346.
PubMed
Larkin A
,
Siddens LK
,
Krueger SK
,
Tilton SC
,
Waters KM
,
Williams DE
, et al.
.
Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin.
Toxicol Appl Pharmacol. 2013 ;267(2):192-9.
PubMed
Matzke MM
,
Allan SE
,
Anderson KA
,
Waters KM
.
An approach for calculating a confidence interval from a single aquatic sample for monitoring hydrophobic organic contaminants.
Environ Toxicol Chem. 2012 ;31(12):2888-92.
PubMed
Motorykin, ii O
,
Matzke MM
,
Waters KM
,
Simonich SLMassey
.
Association of carcinogenic polycyclic aromatic hydrocarbon emissions and smoking with lung cancer mortality rates on a global scale.
Environ Sci Technol. 2013 ;47(7):3410-6.
PubMed
B
Brown J
,
Phillips AR
,
Lewis DA
,
Mans M-A
,
Chang Y
,
Tanguay RL
, et al.
.
Bioinformatics Resource Manager: a systems biology web tool for microRNA and omics data integration.
BMC Bioinformatics. 2019 ;20(1):255.
PubMed
Tilton SC
,
Tal TL
,
Scroggins SM
,
Franzosa JA
,
Peterson ES
,
Tanguay RL
, et al.
.
Bioinformatics Resource Manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools.
BMC Bioinformatics. 2012 ;13:311.
PubMed
C
Knecht AL
,
Goodale BC
,
Truong L
,
Simonich MT
,
Swanson AJ
,
Matzke MM
, et al.
.
Comparative developmental toxicity of environmentally relevant oxygenated PAHs.
Toxicol Appl Pharmacol. 2013 ;271(2):266-75.
PubMed
Teeguarden JG
,
Tan Y-M
,
Edwards SW
,
Leonard JA
,
Anderson KA
,
Corley RA
, et al.
.
Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework.
Environ Sci Technol. 2016 ;50(9):4579-86.
PubMed
Shankar P
,
Geier MC
,
Truong L
,
McClure RS
,
Pande P
,
Waters KM
, et al.
.
Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard.
Int J Mol Sci. 2019 ;20(10).
PubMed
Siddens LK
,
Bunde KL
,
Harper TA
,
McQuistan TJ
,
Löhr CV
,
Bramer LM
, et al.
.
Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.
Toxicol Appl Pharmacol. 2015 ;287(2):149-160.
PubMed
D
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
, et al.
.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
Mol Carcinog. 2017 ;56(1):163-171.
PubMed
E
Chen J
,
Huang C
,
Truong L
,
La Du JK
,
Tilton SC
,
Waters KM
, et al.
.
Early life stage trimethyltin exposure induces ADP-ribosylation factor expression and perturbs the vascular system in zebrafish.
Toxicology. 2012 ;302(2-3):129-39.
PubMed
Forsberg ND
,
Stone D
,
Harding A
,
Harris S
,
Matzke MM
,
Cardenas A
, et al.
.
Effect of Native American fish smoking methods on dietary exposure to polycyclic aromatic hydrocarbons and possible risks to human health.
J Agric Food Chem. 2012 ;60(27):6899-906.
PubMed
Teeguarden JG
,
Tan Y-M
,
Edwards SW
,
Leonard JA
,
Anderson KA
,
Kile ML
, et al.
.
Expanding on Successful Concepts, Models, and Organization.
Environ Sci Technol. 2016 ;50(17):8921-2.
PubMed
G
Saili KS
,
Tilton SC
,
Waters KM
,
Tanguay RL
.
Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17β-estradiol in embryonic zebrafish.
Reprod Toxicol. 2013 ;38:89-101.
PubMed
H
Wittwehr C
,
Aladjov H
,
Ankley G
,
Byrne HJ
,
de Knecht J
,
Heinzle E
, et al.
.
How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology.
Toxicol Sci. 2017 ;155(2):326-336.
PubMed
I
Davie-Martin CL
,
Stratton KG
,
Teeguarden JG
,
Waters KM
,
Simonich SLMassey
.
Implications of Bioremediation of Polycyclic Aromatic Hydrocarbon-Contaminated Soils for Human Health and Cancer Risk.
Environ Sci Technol. 2017 ;51(17):9458-9468.
PubMed
Hobbie KA
,
Peterson ES
,
Barton ML
,
Waters KM
,
Anderson KA
.
Integration of data systems and technology improves research and collaboration for a superfund research center.
J Lab Autom. 2012 ;17(4):275-83.
PubMed
L
Goodale BC
,
La Du JK
,
Tilton SC
,
Sullivan CM
,
Bisson WH
,
Waters KM
, et al.
.
Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs.
Toxicol Sci. 2015 ;147(2):397-411.
PubMed
M
Tilton SC
,
Siddens LK
,
Krueger SK
,
Larkin A
,
Löhr CV
,
Williams DE
, et al.
.
Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential.
Toxicol Sci. 2015 ;146(1):135-45.
PubMed
Tal TL
,
Franzosa JA
,
Tilton SC
,
Philbrick KA
,
Iwaniec UT
,
Turner RT
, et al.
.
MicroRNAs control neurobehavioral development and function in zebrafish.
FASEB J. 2012 ;26(4):1452-61.
PubMed
P
Haggard DE
,
Noyes PD
,
Waters KM
,
Tanguay RL
.
Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish.
Toxicol Appl Pharmacol. 2016 ;308:32-45.
PubMed
Siddens LK
,
Larkin A
,
Krueger SK
,
Bradfield CA
,
Waters KM
,
Tilton SC
, et al.
.
Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse.
Toxicol Appl Pharmacol. 2012 ;264(3):377-86.
PubMed
R
Lafontaine S
,
Schrlau JE
,
Butler J
,
Jia Y
,
Harper B
,
Harris S
, et al.
.
Relative Influence of Trans-Pacific and Regional Atmospheric Transport of PAHs in the Pacific Northwest, U.S.
Environ Sci Technol. 2015 ;49(23):13807-16.
PubMed
Franzosa JA
,
Bugel SM
,
Tal TL
,
La Du JK
,
Tilton SC
,
Waters KM
, et al.
.
Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects.
FASEB J. 2013 ;27(12):4866-76.
PubMed
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