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Cite NIEHS Superfund Support
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In the News
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Our Research
PAH Fate and Exposure
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PAH Health Outcomes
Mechanisms of PAH Susceptibility
PAH Remediation and Transformations
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In the News
Center Publications
Author
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Tammie J McQuistan
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2015
Harper TA
,
Morré J
,
Lauer FT
,
McQuistan TJ
,
Hummel JM
,
Burchiel SW
, et al.
.
Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.
Mutat Res Genet Toxicol Environ Mutagen. 2015 ;782:51-6.
PubMed
Siddens LK
,
Bunde KL
,
Harper TA
,
McQuistan TJ
,
Löhr CV
,
Bramer LM
, et al.
.
Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.
Toxicol Appl Pharmacol. 2015 ;287(2):149-160.
PubMed
Madeen EP
,
Corley RA
,
Crowell SRitger
,
Turteltaub KW
,
Ognibene TJ
,
Malfatti M
, et al.
.
Human in Vivo Pharmacokinetics of [(14)C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Microdosing.
Chem Res Toxicol. 2015 ;28(1):126-34.
PubMed
2016
Madeen EP
,
Ognibene TJ
,
Corley RA
,
McQuistan TJ
,
Henderson MC
,
Baird WM
, et al.
.
Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry.
Chem Res Toxicol. 2016 ;29(10):1641-1650.
PubMed
2018
Hummel JM
,
Madeen EP
,
Siddens LK
,
Uesugi S
,
McQuistan TJ
,
Anderson KA
, et al.
.
Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.
Food Chem Toxicol. 2018 ;115:136-147.
PubMed
2019
Madeen EP
,
Siddens LK
,
Uesugi S
,
McQuistan TJ
,
Corley RA
,
Smith JN
, et al.
.
Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing.
Toxicol Appl Pharmacol. 2019 ;364:97-105.
PubMed