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Journal Article
Pande P, Madeen EP, Williams DE, Crowell SR, Ognibene TJ, Turteltaub KW, et al.. Translating dosimetry of Dibenzo[def,p]chrysene (DBC) and metabolites across dose and species using physiologically based pharmacokinetic (PBPK) modeling. Toxicol Appl Pharmacol. 2021 ;:115830.
Garcia WL, Miller CJ, Lomas GX, Gaither KA, Tyrrell KJ, Brandvold KR, et al.. Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[]pyrene and 1-Nitropyrene Exposure. Chem Res Toxicol. 2022 ;35(4):585-596.
Stoddard EG, Nag S, Martin J, Tyrrell KJ, Gibbins T, Anderson KA, et al.. Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice. Chem Res Toxicol. 2021 ;34(9):2145-2156.
Gaither KA, Pande P. Competitive Metabolism of Polycyclic Aromatic Hydrocarbons (PAHs): An Assessment Using In Vitro Metabolism and Physiologically Based Pharmacokinetic (PBPK) Modeling. Int J Environ Res Public Health. 2022 ;19(14).
Maier MLVermilli, Siddens LK, Pennington JM, Uesugi SL, Anderson KA, Tidwell LG, et al.. Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [C]-BaP. Environ Int. 2022 ;159:107045.
Stoddard EG, Killinger BJ, Nag S, Martin J, Corley RA, Wright AT. Benzo[ a]pyrene Induction of Glutathione S-Transferases: An Activity-Based Protein Profiling Investigation. Chem Res Toxicol. 2019 ;32(6):1259-1267.
Maier MLVermilli, Siddens LK, Uesugi SL, Choi J, Leonard SW, Pennington JM, et al.. 3,3'-Diindolylmethane Exhibits Significant Metabolism after Oral Dosing in Humans. Drug Metab Dispos. 2021 ;49(8):694-705.