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Cite NIEHS Superfund Support
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In the News
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Our Research
PAH Fate and Exposure
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PAH Health Outcomes
Mechanisms of PAH Susceptibility
PAH Remediation and Transformations
Research Cores
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Krueger, Sharon K
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A
Larkin A
,
Siddens LK
,
Krueger SK
,
Tilton SC
,
Waters KM
,
Williams DE
, et al.
.
Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin.
Toxicol Appl Pharmacol. 2013 ;267(2):192-9.
PubMed
C
Siddens LK
,
Bunde KL
,
Harper TA
,
McQuistan TJ
,
Löhr CV
,
Bramer LM
, et al.
.
Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.
Toxicol Appl Pharmacol. 2015 ;287(2):149-160.
PubMed
D
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
, et al.
.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
Mol Carcinog. 2017 ;56(1):163-171.
PubMed
I
Yu Z
,
Löhr CV
,
Fischer KA
,
Louderback MA
,
Krueger SK
,
Dashwood RH
, et al.
.
In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring: role of the aryl hydrocarbon receptor.
Cancer Res. 2006 ;66(2):755-62.
PubMed
M
Tilton SC
,
Siddens LK
,
Krueger SK
,
Larkin A
,
Löhr CV
,
Williams DE
, et al.
.
Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential.
Toxicol Sci. 2015 ;146(1):135-45.
PubMed
P
Hummel JM
,
Madeen EP
,
Siddens LK
,
Uesugi S
,
McQuistan TJ
,
Anderson KA
, et al.
.
Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.
Food Chem Toxicol. 2018 ;115:136-147.
PubMed
Siddens LK
,
Larkin A
,
Krueger SK
,
Bradfield CA
,
Waters KM
,
Tilton SC
, et al.
.
Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse.
Toxicol Appl Pharmacol. 2012 ;264(3):377-86.
PubMed