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In the News
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Our Research
PAH Fate and Exposure
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PAH Health Outcomes
Mechanisms of PAH Susceptibility
PAH Remediation and Transformations
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In the News
Center Publications
Author
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Type
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Carcinogens
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2006
Yu Z
,
Löhr CV
,
Fischer KA
,
Louderback MA
,
Krueger SK
,
Dashwood RH
, et al.
.
In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring: role of the aryl hydrocarbon receptor.
Cancer Res. 2006 ;66(2):755-62.
PubMed
2012
Forsberg ND
,
Stone D
,
Harding A
,
Harris S
,
Matzke MM
,
Cardenas A
, et al.
.
Effect of Native American fish smoking methods on dietary exposure to polycyclic aromatic hydrocarbons and possible risks to human health.
J Agric Food Chem. 2012 ;60(27):6899-906.
PubMed
Shorey LE
,
Castro DJ
,
Baird WM
,
Siddens LK
,
Löhr CV
,
Matzke MM
, et al.
.
Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring.
Cancer Lett. 2012 ;317(1):49-55.
PubMed
2013
Motorykin, ii O
,
Matzke MM
,
Waters KM
,
Simonich SLMassey
.
Association of carcinogenic polycyclic aromatic hydrocarbon emissions and smoking with lung cancer mortality rates on a global scale.
Environ Sci Technol. 2013 ;47(7):3410-6.
PubMed
Shorey LE
,
Madeen EP
,
Atwell LL
,
Ho E
,
Löhr CV
,
Pereira CB
, et al.
.
Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane.
Toxicol Appl Pharmacol. 2013 ;270(1):60-9.
PubMed
Crowell SRitger
,
Sharma AK
,
Amin SG
,
Soelberg JJ
,
Sadler NC
,
Wright AT
, et al.
.
Impact of pregnancy on the pharmacokinetics of dibenzo[def,p]chrysene in mice.
Toxicol Sci. 2013 ;135(1):48-62.
PubMed
2014
Crowell SRitger
,
Hanson-Drury S
,
Williams DE
,
Corley RA
.
In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes.
Toxicol Lett. 2014 ;228(1):48-55.
PubMed
2015
Siddens LK
,
Bunde KL
,
Harper TA
,
McQuistan TJ
,
Löhr CV
,
Bramer LM
, et al.
.
Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.
Toxicol Appl Pharmacol. 2015 ;287(2):149-160.
PubMed
Madeen EP
,
Corley RA
,
Crowell SRitger
,
Turteltaub KW
,
Ognibene TJ
,
Malfatti M
, et al.
.
Human in Vivo Pharmacokinetics of [(14)C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Microdosing.
Chem Res Toxicol. 2015 ;28(1):126-34.
PubMed
Tilton SC
,
Siddens LK
,
Krueger SK
,
Larkin A
,
Löhr CV
,
Williams DE
, et al.
.
Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential.
Toxicol Sci. 2015 ;146(1):135-45.
PubMed
2017
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
, et al.
.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
Mol Carcinog. 2017 ;56(1):163-171.
PubMed
Smith JN
,
Mehinagic D
,
Nag S
,
Crowell SRitger
,
Corley RA
.
In vitro metabolism of benzo[a]pyrene-7,8-dihydrodiol and dibenzo[def,p]chrysene-11,12 diol in rodent and human hepatic microsomes.
Toxicol Lett. 2017 ;269:23-32.
PubMed
2018
Hummel JM
,
Madeen EP
,
Siddens LK
,
Uesugi S
,
McQuistan TJ
,
Anderson KA
, et al.
.
Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.
Food Chem Toxicol. 2018 ;115:136-147.
PubMed