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Author Info
Madeen EP
2022
Pande P, Madeen EP, Williams DE, Crowell SR, Ognibene TJ, Turteltaub KW, Corley RA, Smith JN Translating dosimetry of Dibenzo[def,p]chrysene (DBC) and metabolites across dose and species using physiologically based pharmacokinetic (PBPK) modeling. Toxicol Appl Pharmacol 2022 PubMed PMC9264404
2019
Madeen EP, Siddens LK, Uesugi SL, Mcquistan TJ, Corley RA, Smith JN, Waters KM, Tilton SC, Anderson KA, Ognibene TJ, Turteltaub KW, Williams DE Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing. Toxicol Appl Pharmacol 2019 PubMed PMC6369707
2018
Hummel JM, Madeen EP, Siddens LK, Uesugi SL, Mcquistan TJ, Anderson KA, Turteltaub KW, Ognibene TJ, Bench G, Krueger SK, Harris S, Smith JN, Tilton SC, Baird WM, Williams DE Pharmacokinetics of [(14)C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction. Food Chem Toxicol 2018 PubMed PMC5935529
2017
Madeen EP, Williams DE Environmental PAH exposure and male idiopathic infertility: a review on early life exposures and adult diagnosis. Rev Environ Health 2017 PubMed PMC5454023
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer LM, Waters KM, Williams DE Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. Mol Carcinog 2017 PubMed PMC5457169
2016
Madeen EP, Ognibene TJ, Corley RA, Mcquistan TJ, Henderson MC, Baird WM, Bench G, Turteltaub KW, Williams DE Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry. Chem Res Toxicol 2016 PubMed PMC5380438
2015
Madeen EP, Corley RA, Crowell SR, Turteltaub KW, Ognibene TJ, Malfatti M, Mcquistan TJ, Garrard M, Sudakin DL, Williams DE Human in Vivo Pharmacokinetics of [(14)C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Microdosing. Chem Res Toxicol 2015 PubMed PMC4303324