- PAH Fate and Exposure
- PAH Health Outcomes
- Predicting Toxicity of PAH Mixtures
- PAH Remediation and Transformations
- Virtual Lab Tours
- Sinnhuber Aquatic Research Laboratory Tour
- Publications & Citation
- Publications
- Citation for Publications
Author Info
Waters KM
2025
Mary LS, Mcclure RS, Truong L, Carrell SJ, Waters KM, Tanguay RL Phenotypically anchored transcriptomics across diverse agrichemicals reveals conserved pathways and unique gene expression signatures in zebrafish Front Toxicol 2025 PubMed PMC12575134
Degnan DJ, Bramer LM, Truong L, Tanguay RL, Gosline SJ, Waters KM bmdrc: Python package for quantifying phenotypes from chemical exposures with benchmark dose modeling PLoS Comput Biol 2025 PubMed PMC12313058
Rivera BN, Bramer LM, Ghetu CC, Rohlman D, Adams KT, Waters KM, Anderson KA Investigation of Influences on Indoor and Outdoor SVOC Exposure. Int J Environ Res Public Health 2025 PubMed PMC12027231
2024
Rude CI, Wilson LB, Ladu JK, Lalli PM, Colby SM, Schultz KJ, Smith JN, Waters KM, Tanguay RL Aryl hydrocarbon receptor-dependent toxicity by retene requires metabolic competence. Toxicol Sci 2024 PubMed PMC11514837
Riley KW, Burke K, Dixon HM, Holmes D, Calero L, Barton ML, Miller RL, Bramer LM, Waters KM, Anderson KA, Herbstman JB, Rohlman D Development and Outcomes of Returning Polycyclic Aromatic Hydrocarbon Exposure Results in the Washington Heights, NYC Community. Environ Health Insights 2024 PubMed PMC11271165
Rericha Y, Mary LS, Truong L, Mcclure RS, Martin JK, Leonard SW, Thunga P, Simonich MT, Waters KM, Field JA, Tanguay RL Diverse PFAS produce unique transcriptomic changes linked to developmental toxicity in zebrafish. Front Toxicol 2024 PubMed PMC11298493
Mclarnan SM, Bramer LM, Dixon HM, Scott RP, Calero L, Holmes D, Gibson EA, Cavalier HM, Rohlman D, Miller RL, Kincl LD, Waters KM, Anderson KA, Herbstman JB Predicting personal PAH exposure using high dimensional questionnaire and wristband data. J Expo Sci Environ Epidemiol 2024 PubMed
Colvin VC, Bramer LM, Rivera BN, Pennington JM, Waters KM, Tilton SC Modeling PAH Mixture Interactions in a Human In Vitro Organotypic Respiratory Model. Int J Mol Sci 2024 PubMed PMC11050152
Bramer LM, Dixon HM, Rohlman D, Scott RP, Miller RL, Kincl LD, Herbstman JB, Waters KM, Anderson KA PM(2.5) Is Insufficient to Explain Personal PAH Exposure. Geohealth 2024 PubMed PMC10858395
Bramer LM, Dixon HM, Degnan DJ, Rohlman D, Herbstman JB, Anderson KA, Waters KM Expanding the access of wearable silicone wristbands in community-engaged research through best practices in data analysis and integration. Pac Symp Biocomput 2024 PubMed PMC10766083
2023
Mcclure RS, Rericha Y, Waters KM, Tanguay RL 3' RNA-seq is superior to standard RNA-seq in cases of sparse data but inferior at identifying toxicity pathways in a model organism. Front Bioinform 2023 PubMed PMC10414111
Gosline SJ, Kim DN, Pande P, Thomas DG, Truong L, Hoffman PD, Barton ML, Loftus J, Moran A, Hampton S, Dowson S, Franklin L, Degnan DJ, Anderson LN, Thessen A, Tanguay RL, Anderson KA, Waters KM The Superfund Research Program Analytics Portal: linking environmental chemical exposure to biological phenotypes. Sci Data 2023 PubMed PMC10030892
Rude CI, Tidwell LG, Tilton SC, Waters KM, Anderson KA, Tanguay RL Coupling Environmental Whole Mixture Toxicity Screening with Unbiased RNA-Seq Reveals Site-Specific Biological Responses in Zebrafish. Toxics 2023 PubMed PMC10053777
2022
Wilson LB, Mcclure RS, Waters KM, Simonich MT, Tanguay RL Concentration-response gene expression analysis in zebrafish reveals phenotypically-anchored transcriptional responses to retene. Front Toxicol 2022 PubMed PMC9453431
Shankar P, Garcia GR, Ladu JK, Sullivan CM, Dunham CL, Goodale BC, Waters KM, Stanisheuski S, Maier CS, Thunga P, Reif DM, Tanguay RL The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior. Toxicol Sci 2022 PubMed PMC9308396
Dixon HM, Bramer LM, Scott RP, Calero L, Holmes D, Gibson EA, Cavalier HM, Rohlman D, Miller RL, Calafat AM, Kincl LD, Waters KM, Herbstman JB, Anderson KA Evaluating predictive relationships between wristbands and urine for assessment of personal PAH exposure. Environ Int 2022 PubMed PMC8978533
2021
Shankar P, Mcclure RS, Waters KM, Tanguay RL Gene co-expression network analysis in zebrafish reveals chemical class specific modules. BMC Genomics 2021 PubMed PMC8438978
Mansouri K, Karmaus AL, Fitzpatrick J, Patlewicz G, Pradeep P, Alberga D, Alepee N, Allen TE, Allen D, Alves VM, Andrade CH, Auernhammer TR, Ballabio D, Bell S, Benfenati E, Bhattacharya S, Bastos JV, Boyd S, Brown J, Capuzzi SJ, Chushak Y, Ciallella H, Clark AM, Consonni V, Daga PR, Ekins S, Farag S, Fedorov M, Fourches D, Gadaleta D, Gao F, Gearhart JM, Goh G, Goodman JM, Grisoni F, Grulke CM, Hartung T, Hirn M, Karpov P, Korotcov A, Lavado GJ, Lawless M, Li X, Luechtefeld T, Lunghini F, Mangiatordi GF, Marcou G, Marsh D, Martin T, Mauri A, Muratov EN, Myatt GJ, Nguyen D, Nicolotti O, Note R, Pande P, Parks AK, Peryea T, Polash AH, Rallo R, Roncaglioni A, Rowlands C, Ruiz P, Russo DP, Sayed A, Sayre R, Sheils T, Siegel C, Silva AC, Simeonov A, Sosnin S, Southall N, Strickland J, Tang Y, Teppen B, Tetko IV, Thomas DG, Tkachenko V, Todeschini R, Toma C, Tripodi I, Trisciuzzi D, Tropsha A, Varnek A, Vukovic K, Wang Z, Wang L, Waters KM, Wedlake AJ, Wijeyesakere SJ, Wilson D, Xiao Z, Yang H, Zahoranszky-kohalmi G, Zakharov AV, Zhang FF, Zhang Z, Zhao T, Zhu H, Zorn KM, Casey W, Kleinstreuer NC CATMoS: Collaborative Acute Toxicity Modeling Suite. Environ Health Perspect 2021 PubMed PMC8086800
2020
Truong L, Marvel S, Reif DM, Thomas DG, Pande P, Dasgupta S, Simonich MT, Waters KM, Tanguay RL The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity. Reprod Toxicol 2020 PubMed PMC7892636
2019
Messier KP, Tidwell LG, Ghetu CC, Rohlman D, Scott RP, Bramer LM, Dixon HM, Waters KM, Anderson KA Indoor versus Outdoor Air Quality during Wildfires. Environ Sci Technol Lett 2019 PubMed PMC7039657
Shankar P, Geier MC, Truong L, Mcclure RS, Pande P, Waters KM, Tanguay RL Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard. Int J Mol Sci 2019 PubMed PMC6566387
Brown JM, Phillips AR, Lewis DA, Mans M, Chang Y, Tanguay RL, Peterson ES, Waters KM, Tilton SC Bioinformatics Resource Manager: a systems biology web tool for microRNA and omics data integration. BMC Bioinformatics 2019 PubMed PMC6525352
Madeen EP, Siddens LK, Uesugi SL, Mcquistan TJ, Corley RA, Smith JN, Waters KM, Tilton SC, Anderson KA, Ognibene TJ, Turteltaub KW, Williams DE Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing. Toxicol Appl Pharmacol 2019 PubMed PMC6369707
Dixon HM, Armstrong G, Barton ML, Bergmann AJ, Bondy M, Halbleib ML, Hamilton WJ, Haynes EN, Herbstman JB, Hoffman PD, Jepson PC, Kile ML, Kincl LD, Laurienti PJ, North PE, Paulik LB, Petrosino JF, Points GL, Poutasse CM, Rohlman D, Scott RP, Smith BW, Tidwell LG, Walker CL, Waters KM, Anderson KA Discovery of common chemical exposures across three continents using silicone wristbands. R Soc Open Sci 2019 PubMed PMC6408398
Thomas DG, Shankaran H, Truong L, Tanguay RL, Waters KM Time-dependent behavioral data from zebrafish reveals novel signatures of chemical toxicity using point of departure analysis. Comput Toxicol 2019 PubMed PMC6726397
2018
Dixon HM, Scott RP, Holmes D, Calero L, Kincl LD, Waters KM, Camann DE, Calafat AM, Herbstman JB, Anderson KA Silicone wristbands compared with traditional polycyclic aromatic hydrocarbon exposure assessment methods. Anal Bioanal Chem 2018 PubMed PMC5910488
Haggard DE, Noyes PD, Waters KM, Tanguay RL Transcriptomic and phenotypic profiling in developing zebrafish exposed to thyroid hormone receptor agonists. Reprod Toxicol 2018 PubMed PMC5878140
2017
Davie-martin CL, Stratton KG, Teeguarden JG, Waters KM, Simonich SL Implications of Bioremediation of Polycyclic Aromatic Hydrocarbon-Contaminated Soils for Human Health and Cancer Risk. Environ Sci Technol 2017 PubMed PMC10224095
Wittwehr C, Aladjov H, Ankley G, Byrne HJ, Knecht JD, Heinzle E, Klambauer G, Landesmann B, Luijten M, Mackay C, Maxwell G, Meek ME, Paini A, Perkins E, Sobanski T, Villeneuve D, Waters KM, Whelan M How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology. Toxicol Sci 2017 PubMed PMC5340205
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer LM, Waters KM, Williams DE Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. Mol Carcinog 2017 PubMed PMC5457169
2016
Haggard DE, Noyes PD, Waters KM, Tanguay RL Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish. Toxicol Appl Pharmacol 2016 PubMed PMC5023494
Teeguarden JG, Tan Y, Edwards SW, Leonard JA, Anderson KA, Corley RA, Kile ML, Simonich SL, Stone DL, Tanguay RL, Waters KM, Harper SL, Williams DE Expanding on Successful Concepts, Models, and Organization. Environ Sci Technol 2016 PubMed
Teeguarden JG, Tan Y, Edwards SW, Leonard JA, Anderson KA, Corley RA, Kile ML, Simonich SL, Stone DL, Tanguay RL, Waters KM, Harper SL, Williams DE Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework. Environ Sci Technol 2016 PubMed PMC4854780
2015
Lafontaine S, Schrlau JE, Butler J, Jia Y, Harper B, Harris S, Bramer LM, Waters KM, Harding AK, Simonich SL Relative Influence of Trans-Pacific and Regional Atmospheric Transport of PAHs in the Pacific Northwest, U.S. Environ Sci Technol 2015 PubMed PMC4666789
Goodale BC, La Du JK, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs. Toxicol Sci 2015 PubMed PMC4612346
Siddens LK, Bunde KL, Harper TA, Mcquistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE, Baird WM Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse. Toxicol Appl Pharmacol 2015 PubMed PMC4689210
Tilton SC, Siddens LK, Krueger SK, Larkin AJ, Löhr CV, Williams DE, Baird WM, Waters KM Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential. Toxicol Sci 2015 PubMed PMC4476464
2013
Franzosa JA, Bugel SM, Tal TL, Ladu JK, Tilton SC, Waters KM, Tanguay RL Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects. FASEB J 2013 PubMed PMC3834785
Goodale BC, Tilton SC, Corvi MM, Wilson GR, Janszen DB, Anderson KA, Waters KM, Tanguay RL Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish. Toxicol Appl Pharmacol 2013 PubMed PMC4098828
Knecht AL, Goodale BC, Truong L, Simonich MT, Swanson AJ, Matzke MM, Anderson KA, Waters KM, Tanguay RL Comparative developmental toxicity of environmentally relevant oxygenated PAHs. Toxicol Appl Pharmacol 2013 PubMed PMC3976560
Saili KS, Tilton SC, Waters KM, Tanguay RL Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17β-estradiol in embryonic zebrafish. Reprod Toxicol 2013 PubMed PMC3690774
Motorykin O, Matzke MM, Waters KM, Simonich SL Association of carcinogenic polycyclic aromatic hydrocarbon emissions and smoking with lung cancer mortality rates on a global scale. Environ Sci Technol 2013 PubMed PMC3634325
Truong L, Tilton SC, Zaikova T, Richman E, Waters KM, Hutchison JE, Tanguay RL Surface functionalities of gold nanoparticles impact embryonic gene expression responses. Nanotoxicology 2013 PubMed PMC3399027
Larkin AJ, Siddens LK, Krueger SK, Tilton SC, Waters KM, Williams DE, Baird WM Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin. Toxicol Appl Pharmacol 2013 PubMed PMC3626406
2012
Chen J, Huang C, Truong L, Ladu JK, Tilton SC, Waters KM, Lin K, Tanguay RL, Dong Q Early life stage trimethyltin exposure induces ADP-ribosylation factor expression and perturbs the vascular system in zebrafish. Toxicology 2012 PubMed PMC3511642
Matzke MM, Allan SE, Anderson KA, Waters KM An approach for calculating a confidence interval from a single aquatic sample for monitoring hydrophobic organic contaminants. Environ Toxicol Chem 2012 PubMed PMC3581149
Tilton SC, Tal TL, Scroggins SM, Franzosa JA, Peterson ES, Tanguay RL, Waters KM Bioinformatics Resource Manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools. BMC Bioinformatics 2012 PubMed PMC3534564
Siddens LK, Larkin AJ, Krueger SK, Bradfield CA, Waters KM, Tilton SC, Pereira CB, Löhr CV, Arlt VM, Phillips DH, Williams DE, Baird WM Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicol Appl Pharmacol 2012 PubMed PMC3483092
Hobbie KA, Peterson ES, Barton ML, Waters KM, Anderson KA Integration of data systems and technology improves research and collaboration for a superfund research center. J Lab Autom 2012 PubMed PMC3460553
Forsberg ND, Stone DL, Harding AK, Harper B, Harris S, Matzke MM, Cardenas A, Waters KM, Anderson KA Effect of Native American fish smoking methods on dietary exposure to polycyclic aromatic hydrocarbons and possible risks to human health. J Agric Food Chem 2012 PubMed PMC3567306
Shorey LE, Castro DJ, Baird WM, Siddens LK, Löhr CV, Matzke MM, Waters KM, Corley RA, Williams DE Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring. Cancer Lett 2012 PubMed PMC3269513