Author Title Type [ Year(Asc)]
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2023
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Tilton SC, Vertel EA, Tidwell LG, et al.. Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts. Toxicol Appl Pharmacol. 2023 ;460:116377.
Rude CI, Tidwell LG, Tilton SC, Waters KM, Anderson KA, Tanguay RL. Coupling Environmental Whole Mixture Toxicity Screening with Unbiased RNA-Seq Reveals Site-Specific Biological Responses in Zebrafish. Toxics. 2023 ;11(3).
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Labut EM, Vertel EA, Tidwell LG, et al.. Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing. Chem Biol Interact. 2023 ;382:110608.
2022
Monica L Vermillion Maier, Siddens LK, Pennington JM, Uesugi S, Anderson KA, Tidwell LG, Ognibene TJ, et al.. Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [C]-BaP. Environ Int. 2022 ;159:107045.
Rivera BN, Wilson LB, Kim DNam, Pande P, Anderson KA, Tilton SC, et al.. A Comparative Multi-System Approach to Characterizing Bioactivity of Commonly Occurring Chemicals. Int J Environ Res Public Health. 2022 ;19(7).
Rivera BN, Ghetu C, Chang Y, Truong L, Tanguay RL, Anderson KA, et al.. Leveraging Multiple Data Streams for Prioritization of Mixtures for Hazard Characterization. Toxics. 2022 ;10(11).
2021
Monica L Vermillion Maier, Siddens LK, Uesugi S, Choi J, Leonard SW, Pennington JM, Smith JN, et al.. 3,3'-Diindolylmethane Exhibits Significant Metabolism after Oral Dosing in Humans. Drug Metab Dispos. 2021 ;49(8):694-705.
Chang Y, Rager JE, Tilton SC. Linking Coregulated Gene Modules with Polycyclic Aromatic Hydrocarbon-Related Cancer Risk in the 3D Human Bronchial Epithelium. Chem Res Toxicol. 2021 ;34(6):1445-1455.
2020
Garland MA, Geier MC, Bugel SM, Shankar P, Dunham CL, Brown J, et al.. Aryl hydrocarbon receptor mediates larval zebrafish fin duplication following exposure to benzofluoranthenes. Toxicol Sci. 2020 ;.
Chang Y, Huynh CThanh Thu, Bastin KM, Rivera BN, Siddens LK, Tilton SC. Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures. Toxicol In Vitro. 2020 ;69:104991.
2019
Brown J, Phillips AR, Lewis DA, Mans M-A, Chang Y, Tanguay RL, et al.. Bioinformatics Resource Manager: a systems biology web tool for microRNA and omics data integration. BMC Bioinformatics. 2019 ;20(1):255.
Chang Y, Siddens LK, Heine LK, Sampson DA, Yu Z, Fischer KA, et al.. Comparative mechanisms of PAH toxicity by benzo[a]pyrene and dibenzo[def,p]chrysene in primary human bronchial epithelial cells cultured at air-liquid interface. Toxicol Appl Pharmacol. 2019 ;:114644.
Madeen EP, Siddens LK, Uesugi S, McQuistan TJ, Corley RA, Smith JN, et al.. Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing. Toxicol Appl Pharmacol. 2019 ;364:97-105.
2018
Hummel JM, Madeen EP, Siddens LK, Uesugi S, McQuistan TJ, Anderson KA, et al.. Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction. Food Chem Toxicol. 2018 ;115:136-147.
Garcia GR, Shankar P, Dunham CL, Garcia A, La Du JK, Truong L, et al.. Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA ( slincR) Using the Zebrafish Model. Environ Health Perspect. 2018 ;126(11):117002.
Geier MC, D Minick J, Truong L, Tilton SC, Pande P, Anderson KA, et al.. Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish. Toxicol Appl Pharmacol. 2018 ;354:115-125.
2017
Curtis LR, Bravo CF, Bayne CJ, Tilton F, Arkoosh MR, Lambertini E, et al.. Transcriptional changes in innate immunity genes in head kidneys from Aeromonas salmonicida-challenged rainbow trout fed a mixture of polycyclic aromatic hydrocarbons. Ecotoxicol Environ Saf. 2017 ;142:157-163.
2015
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, et al.. Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse. Toxicol Appl Pharmacol. 2015 ;287(2):149-160.
Goodale BC, La Du JK, Tilton SC, Sullivan CM, Bisson WH, Waters KM, et al.. Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs. Toxicol Sci. 2015 ;147(2):397-411.
Tilton SC, Siddens LK, Krueger SK, Larkin A, Löhr CV, Williams DE, et al.. Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential. Toxicol Sci. 2015 ;146(1):135-45.
2014
Chen J, Tanguay RL, Tal TL, Gai Z, Ma X, Bai C, et al.. Early life perfluorooctanesulphonic acid (PFOS) exposure impairs zebrafish organogenesis. Aquat Toxicol. 2014 ;150:124-32.
2013
Larkin A, Siddens LK, Krueger SK, Tilton SC, Waters KM, Williams DE, et al.. Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin. Toxicol Appl Pharmacol. 2013 ;267(2):192-9.
Saili KS, Tilton SC, Waters KM, Tanguay RL. Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17β-estradiol in embryonic zebrafish. Reprod Toxicol. 2013 ;38:89-101.
Franzosa JA, Bugel SM, Tal TL, La Du JK, Tilton SC, Waters KM, et al.. Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects. FASEB J. 2013 ;27(12):4866-76.
Goodale BC, Tilton SC, Corvi MM, Wilson G, Janszen DB, Anderson KA, et al.. Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish. Toxicol Appl Pharmacol. 2013 ;272(3):656-70.

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