Author Info

Truong L

2025

Mary LS, Mcclure RS, Truong L, Carrell SJ, Waters KM, Tanguay RL Phenotypically anchored transcriptomics across diverse agrichemicals reveals conserved pathways and unique gene expression signatures in zebrafish Front Toxicol 2025 PubMed PMC12575134
Morshead ML, Truong L, Carrell SJ, Scott RP, Anderson KA, Tanguay RL Chemical structure drives developmental toxicity of alkyl-substituted naphthalenes in zebrafish Environment International 2025 PubMed PMC12560828
Degnan DJ, Bramer LM, Truong L, Tanguay RL, Gosline SJ, Waters KM bmdrc: Python package for quantifying phenotypes from chemical exposures with benchmark dose modeling PLoS Comput Biol 2025 PubMed PMC12313058
Morshead ML, Truong L, Simonich MT, Moran JE, Anderson KA, Tanguay RL Developmental toxicity of alkylated PAHs and substituted phenanthrenes: Structural nuances drive diverse toxicity and AHR activation. Chemosphere 2025 PubMed PMC11732715
Huizenga JM, Truong L, Semprini L Rapid determination of chemical losses in a microplate bioassay using fluorescence spectroscopy. Anal Methods 2025 PubMed PMC11806944

2024

Rericha Y, Mary LS, Truong L, Mcclure RS, Martin JK, Leonard SW, Thunga P, Simonich MT, Waters KM, Field JA, Tanguay RL Diverse PFAS produce unique transcriptomic changes linked to developmental toxicity in zebrafish. Front Toxicol 2024 PubMed PMC11298493
Stagaman K, Alexiev A, Sieler MJ, Hammer A, Kasschau KD, Truong L, Tanguay RL, Sharpton TJ The zebrafish gut microbiome influences benzo[a]pyrene developmental neurobehavioral toxicity. Sci Rep 2024 PubMed PMC11199668
Huizenga JM, Schindler J, Simonich MT, Truong L, Garcia-jaramillo M, Tanguay RL, Semprini L PAH bioremediation with Rhodococcus rhodochrous ATCC 21198: Impact of cell immobilization and surfactant use on PAH treatment and post-remediation toxicity. J Hazard Mater 2024 PubMed PMC11042972

2023

Rericha Y, Simonich MT, Truong L, Tanguay RL Review of the zebrafish as a model to investigate per- and polyfluoroalkyl substance toxicity. Toxicol Sci 2023 PubMed PMC10375317
Gosline SJ, Kim DN, Pande P, Thomas DG, Truong L, Hoffman PD, Barton ML, Loftus J, Moran A, Hampton S, Dowson S, Franklin L, Degnan DJ, Anderson LN, Thessen A, Tanguay RL, Anderson KA, Waters KM The Superfund Research Program Analytics Portal: linking environmental chemical exposure to biological phenotypes. Sci Data 2023 PubMed PMC10030892

2022

Thunga P, Truong L, Rericha Y, Ladu JK, Morshead ML, Tanguay RL, Reif DM Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure. Toxics 2022 PubMed PMC9781692
Rivera BN, Ghetu CC, Chang Y, Truong L, Tanguay RL, Anderson KA, Tilton SC Leveraging Multiple Data Streams for Prioritization of Mixtures for Hazard Characterization. Toxics 2022 PubMed PMC9699527
Rericha Y, Truong L, Leong C, Cao D, Field JA, Tanguay RL Dietary Perfluorohexanoic Acid (PFHxA) Exposures in Juvenile Zebrafish Produce Subtle Behavioral Effects across Generations. Toxics 2022 PubMed PMC9319656
Wallis DJ, Ladu JK, Thunga P, Elson DJ, Truong L, Kolluri SK, Tanguay RL, Reif DM Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model. Front Toxicol 2022 PubMed PMC9098949

2021

Thunga P, Truong L, Tanguay RL, Reif DM Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification. Front Toxicol 2021 PubMed PMC8915815
Dasgupta S, Dunham CL, Truong L, Simonich MT, Sullivan CM, Tanguay RL Phenotypically Anchored mRNA and miRNA Expression Profiling in Zebrafish Reveals Flame Retardant Chemical Toxicity Networks. Front Cell Dev Biol 2021 PubMed PMC8063052
Wallis DJ, Truong L, Ladu JK, Tanguay RL, Reif DM Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions. Toxics 2021 PubMed PMC8067468
Guan X, Truong L, Lomnicki SM, Tanguay RL, Cormier SA Developmental Hazard of Environmentally Persistent Free Radicals and Protective Effect of TEMPOL in Zebrafish Model. Toxics 2021 PubMed PMC7829864
Shankar P, Dashner-titus EJ, Truong L, Hayward K, Hudson LG, Tanguay RL Developmental toxicity in zebrafish (Danio rerio) exposed to uranium: A comparison with lead, cadmium, and iron. Environ Pollut 2021 PubMed PMC7785642

2020

Wilson LB, Truong L, Simonich MT, Tanguay RL Systematic Assessment of Exposure Variations on Observed Bioactivity in Zebrafish Chemical Screening. Toxics 2020 PubMed PMC7712973
Truong L, Marvel S, Reif DM, Thomas DG, Pande P, Dasgupta S, Simonich MT, Waters KM, Tanguay RL The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity. Reprod Toxicol 2020 PubMed PMC7892636
Shen Q, Truong L, Simonich MT, Huang C, Tanguay RL, Dong Q Rapid well-plate assays for motor and social behaviors in larval zebrafish. Behav Brain Res 2020 PubMed PMC7341899

2019

Shankar P, Geier MC, Truong L, Mcclure RS, Pande P, Waters KM, Tanguay RL Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard. Int J Mol Sci 2019 PubMed PMC6566387
Trine LS, Davis EL, Roper C, Truong L, Tanguay RL, Simonich SL Formation of PAH Derivatives and Increased Developmental Toxicity during Steam Enhanced Extraction Remediation of Creosote Contaminated Superfund Soil. Environ Sci Technol 2019 PubMed PMC7103206
Thomas DG, Shankaran H, Truong L, Tanguay RL, Waters KM Time-dependent behavioral data from zebrafish reveals novel signatures of chemical toxicity using point of departure analysis. Comput Toxicol 2019 PubMed PMC6726397
Hagstrom D, Truong L, Zhang S, Tanguay RL, Collins ES Comparative Analysis of Zebrafish and Planarian Model Systems for Developmental Neurotoxicity Screens Using an 87-Compound Library. Toxicol Sci 2019 PubMed PMC6317421

2018

Garcia GR, Shankar P, Dunham CL, Garcia A, Ladu JK, Truong L, Tilton SC, Tanguay RL Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA (slincR) Using the Zebrafish Model. Environ Health Perspect 2018 PubMed PMC6371766
Geier MC, Minick DJ, Truong L, Tilton SC, Pande P, Anderson KA, Teeguarden JG, Tanguay RL Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish. Toxicol Appl Pharmacol 2018 PubMed PMC6087484
Balik-meisner M, Truong L, Scholl EH, Ladu JK, Tanguay RL, Reif DM Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure. Environ Health Perspect 2018 PubMed PMC6084885
Garcia GR, Bugel SM, Truong L, Spagnoli S, Tanguay RL AHR2 required for normal behavioral responses and proper development of the skeletal and reproductive systems in zebrafish. PLoS One 2018 PubMed PMC5832240
Geier MC, Chlebowski AC, Truong L, Simonich SL, Anderson KA, Tanguay RL Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons. Arch Toxicol 2018 PubMed PMC5820187
Balik-meisner M, Truong L, Scholl EH, Tanguay RL, Reif DM Population genetic diversity in zebrafish lines. Mamm Genome 2018 PubMed PMC5851690

2017

Knecht AL, Truong L, Marvel SW, Reif DM, Garcia A, Lu C, Simonich MT, Teeguarden JG, Tanguay RL Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish. Toxicol Appl Pharmacol 2017 PubMed PMC5539966
Schrlau JE, Kramer AL, Chlebowski AC, Truong L, Tanguay RL, Simonich SL, Semprini L Formation of Developmentally Toxic Phenanthrene Metabolite Mixtures by Mycobacterium sp. ELW1. Environ Sci Technol 2017 PubMed PMC5996983
Chlebowski AC, Garcia GR, Ladu JK, Bisson WH, Truong L, Simonich SL, Tanguay RL Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs. Toxicol Sci 2017 PubMed PMC5414855
Chlebowski AC, Ladu JK, Truong L, Simonich SL, Tanguay RL Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing. Toxicol Rep 2017 PubMed PMC5527975
Zhang G, Truong L, Tanguay RL, Reif DM A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish. PLoS One 2017 PubMed PMC5242475
Knecht AL, Truong L, Simonich MT, Tanguay RL Developmental benzo[a]pyrene (B[a]P) exposure impacts larval behavior and impairs adult learning in zebrafish. Neurotoxicol Teratol 2017 PubMed PMC5235990
Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades. Toxicol Appl Pharmacol 2017 PubMed PMC5224523

2016

Truong L, Bugel SM, Chlebowski AC, Usenko CY, Simonich MT, Simonich SL, Tanguay RL Optimizing multi-dimensional high throughput screening using zebrafish. Reprod Toxicol 2016 PubMed PMC5067206
Truong L, Simonich MT, Tanguay RL Better, Faster, Cheaper: Getting the Most Out of High-Throughput Screening with Zebrafish. Methods Mol Biol 2016 PubMed
Zhang G, Marvel S, Truong L, Tanguay RL, Reif DM Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure. Reprod Toxicol 2016 PubMed PMC4905797
Reif DM, Truong L, Mandrell D, Marvel S, Zhang G, Tanguay RL High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes. Arch Toxicol 2016 PubMed PMC4701642
Titaley IA, Chlebowski AC, Truong L, Tanguay RL, Simonich SL Identification and Toxicological Evaluation of Unsubstituted PAHs and Novel PAH Derivatives in Pavement Sealcoat Products. Environ Sci Technol Lett 2016 PubMed PMC6075666

2014

Truong L, Mandrell D, Mandrell R, Simonich MT, Tanguay RL A rapid throughput approach identifies cognitive deficits in adult zebrafish from developmental exposure to polybrominated flame retardants. Neurotoxicology 2014 PubMed PMC4134748
Truong L, Reif DM, Mary LS, Geier MC, Truong HD, Tanguay RL Multidimensional in vivo hazard assessment using zebrafish. Toxicol Sci 2014 PubMed PMC3871932

2013

Knecht AL, Goodale BC, Truong L, Simonich MT, Swanson AJ, Matzke MM, Anderson KA, Waters KM, Tanguay RL Comparative developmental toxicity of environmentally relevant oxygenated PAHs. Toxicol Appl Pharmacol 2013 PubMed PMC3976560
Truong L, Denardo MA, Kundu S, Collins TJ, Tanguay RL Zebrafish Assays as Developmental Toxicity Indicators in The Design of TAML Oxidation Catalysts. Green Chem 2013 PubMed PMC3989102
Truong L, Tilton SC, Zaikova T, Richman E, Waters KM, Hutchison JE, Tanguay RL Surface functionalities of gold nanoparticles impact embryonic gene expression responses. Nanotoxicology 2013 PubMed PMC3399027
Adenuga AA, Truong L, Tanguay RL, Remcho VT Preparation of water soluble carbon nanotubes and assessment of their biological activity in embryonic zebrafish. Int J Biomed Nanosci Nanotechnol 2013 PubMed PMC4349379

2012

Chen J, Huang C, Truong L, Ladu JK, Tilton SC, Waters KM, Lin K, Tanguay RL, Dong Q Early life stage trimethyltin exposure induces ADP-ribosylation factor expression and perturbs the vascular system in zebrafish. Toxicology 2012 PubMed PMC3511642
Mandrell D, Truong L, Jephson C, Sarker MR, Moore A, Lang C, Simonich MT, Tanguay RL Automated zebrafish chorion removal and single embryo placement: optimizing throughput of zebrafish developmental toxicity screens. J Lab Autom 2012 PubMed PMC3327291