Author Info

Tanguay RL

2026

Karchner SI, Aluru N, Franks DG, Mandl CA, Goldstone JV, Burke T, Champlin D, Ladu JK, Perone DM, Stinson S, Truong L, Clark BW, Nacci D, Tanguay RL, Hahn ME Using fish models to understand the role of aryl hydrocarbon receptor (AHR)-interacting protein (AIP) in controlling sensitivity and resistance to dioxin-like compounds in vivo. Toxicol Sci PubMed PMC13035081

Morshead ML, Truong L, Tanguay RL Position-specific methyl substitution on benzo[a]pyrene drives AHR-dependent fin duplication in zebrafish. Toxicol Sci PubMed PMC12826582

2025

Mary LS, Mcclure RS, Truong L, Carrell SJ, Waters KM, Tanguay RL Phenotypically anchored transcriptomics across diverse agrichemicals reveals conserved pathways and unique gene expression signatures in zebrafish Front Toxicol PubMed PMC12575134

Morshead ML, Truong L, Carrell SJ, Scott RP, Anderson KA, Tanguay RL Chemical structure drives developmental toxicity of alkyl-substituted naphthalenes in zebrafish Environment International PubMed PMC12560828

Degnan DJ, Bramer LM, Truong L, Tanguay RL, Gosline SJ, Waters KM bmdrc: Python package for quantifying phenotypes from chemical exposures with benchmark dose modeling PLoS Comput Biol PubMed PMC12313058

Rude CI, Smith JN, Scott RP, Schultz KJ, Anderson KA, Tanguay RL A mixture parameterized biologically based dosimetry model to predict body burdens of polycyclic aromatic hydrocarbons in developmental zebrafish toxicity assays. Toxicol Sci PubMed PMC12118961

Morshead ML, Tanguay RL Advancements in the Developmental Zebrafish Model for Predictive Human Toxicology. Curr Opin Toxicol PubMed PMC11780918

Perone DM, Annalora AJ, Goldstone JV, Dickey AN, Salanga MC, Francolini RD, Wright FA, Marcus CB, Tanguay RL, Garcia-jaramillo M Zebrafish Cyp1b1 knockout alters eye and brain metabolomic profiles, affecting ocular and neurobehavioral function. Toxicol Appl Pharmacol PubMed PMC12083501

Morshead ML, Truong L, Simonich MT, Moran JE, Anderson KA, Tanguay RL Developmental toxicity of alkylated PAHs and substituted phenanthrenes: Structural nuances drive diverse toxicity and AHR activation. Chemosphere PubMed PMC11732715

2024

Rude CI, Wilson LB, Ladu JK, Lalli PM, Colby SM, Schultz KJ, Smith JN, Waters KM, Tanguay RL Aryl hydrocarbon receptor-dependent toxicity by retene requires metabolic competence. Toxicol Sci PubMed PMC11514837

Stagaman K, Alexiev A, Sieler MJ, Hammer A, Kasschau KD, Truong L, Tanguay RL, Sharpton TJ The zebrafish gut microbiome influences benzo[a]pyrene developmental neurobehavioral toxicity. Sci Rep PubMed PMC11199668

Huizenga JM, Schindler J, Simonich MT, Truong L, Garcia-jaramillo M, Tanguay RL, Semprini L PAH bioremediation with Rhodococcus rhodochrous ATCC 21198: Impact of cell immobilization and surfactant use on PAH treatment and post-remediation toxicity. J Hazard Mater PubMed PMC11042972

Dasgupta S, Goodale BC, Tanguay RL Single cell sequencing of zebrafish kidney marrows reveals AHR2-dependent endogenous regulation of hematopoiesis. bioRxiv PubMed PMC11071399

2023

Dasgupta S, Ladu JK, Garcia GR, Li S, Tomono-duval K, Rericha Y, Huang L, Tanguay RL A CRISPR-Cas9 mutation in sox9b long intergenic noncoding RNA (slincR) affects zebrafish development, behavior, and regeneration. Toxicol Sci PubMed PMC10375313

Rericha Y, Simonich MT, Truong L, Tanguay RL Review of the zebrafish as a model to investigate per- and polyfluoroalkyl substance toxicity. Toxicol Sci PubMed PMC10375317

Wilson LB, Moran IL, Anderson KA, Tanguay RL Advances in PAH mixture toxicology enabled by zebrafish. Curr Opin Toxicol PubMed PMC10292781

Nguyen BD, Stevens BL, Elson DJ, Finlay D, Gamble JT, Kopparapu PR, Tanguay RL, Buermeyer AB, Kerkvliet NI, Kolluri SK 11-Cl-BBQ, a select modulator of AhR-regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27(Kip1). FEBS J PubMed PMC10807707

Rude CI, Tidwell LG, Tilton SC, Waters KM, Anderson KA, Tanguay RL Coupling Environmental Whole Mixture Toxicity Screening with Unbiased RNA-Seq Reveals Site-Specific Biological Responses in Zebrafish. Toxics PubMed PMC10053777

2022

Thunga P, Truong L, Rericha Y, Ladu JK, Morshead ML, Tanguay RL, Reif DM Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure. Toxics PubMed PMC9781692

Rivera BN, Ghetu CC, Chang Y, Truong L, Tanguay RL, Anderson KA, Tilton SC Leveraging Multiple Data Streams for Prioritization of Mixtures for Hazard Characterization. Toxics PubMed PMC9699527

Anderson AL, Dubanksy BD, Wilson LB, Tanguay RL, Rice CD Development and Applications of a Zebrafish (Danio rerio) CYP1A-Targeted Monoclonal Antibody (CRC4) with Reactivity across Vertebrate Taxa: Evidence for a Conserved CYP1A Epitope. Toxics PubMed PMC9320060

Rericha Y, Truong L, Leong C, Cao D, Field JA, Tanguay RL Dietary Perfluorohexanoic Acid (PFHxA) Exposures in Juvenile Zebrafish Produce Subtle Behavioral Effects across Generations. Toxics PubMed PMC9319656

Shankar P, Garcia GR, Ladu JK, Sullivan CM, Dunham CL, Goodale BC, Waters KM, Stanisheuski S, Maier CS, Thunga P, Reif DM, Tanguay RL The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior. Toxicol Sci PubMed PMC9308396

Rivera BN, Wilson LB, Kim DN, Pande P, Anderson KA, Tilton SC, Tanguay RL A Comparative Multi-System Approach to Characterizing Bioactivity of Commonly Occurring Chemicals. Int J Environ Res Public Health PubMed PMC8998123

2021

Shankar P, Mcclure RS, Waters KM, Tanguay RL Gene co-expression network analysis in zebrafish reveals chemical class specific modules. BMC Genomics PubMed PMC8438978

Wallis DJ, Truong L, Ladu JK, Tanguay RL, Reif DM Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions. Toxics PubMed PMC8067468

Guan X, Truong L, Lomnicki SM, Tanguay RL, Cormier SA Developmental Hazard of Environmentally Persistent Free Radicals and Protective Effect of TEMPOL in Zebrafish Model. Toxics PubMed PMC7829864

Shankar P, Dashner-titus EJ, Truong L, Hayward K, Hudson LG, Tanguay RL Developmental toxicity in zebrafish (Danio rerio) exposed to uranium: A comparison with lead, cadmium, and iron. Environ Pollut PubMed PMC7785642

2020

Shankar P, Dasgupta S, Hahn ME, Tanguay RL A Review of the Functional Roles of the Zebrafish Aryl Hydrocarbon Receptors. Toxicol Sci PubMed PMC7706399

Wilson LB, Truong L, Simonich MT, Tanguay RL Systematic Assessment of Exposure Variations on Observed Bioactivity in Zebrafish Chemical Screening. Toxics PubMed PMC7712973

Truong L, Marvel S, Reif DM, Thomas DG, Pande P, Dasgupta S, Simonich MT, Waters KM, Tanguay RL The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity. Reprod Toxicol PubMed PMC7892636

Shen Q, Truong L, Simonich MT, Huang C, Tanguay RL, Dong Q Rapid well-plate assays for motor and social behaviors in larval zebrafish. Behav Brain Res PubMed PMC7341899

Garland MA, Geier MC, Bugel SM, Shankar P, Dunham CL, Brown JM, Tilton SC, Tanguay RL Aryl Hydrocarbon Receptor Mediates Larval Zebrafish Fin Duplication Following Exposure to Benzofluoranthenes. Toxicol Sci PubMed PMC7357178

Roper C, Perez A, Barrett D, Hystad P, Simonich SL, Tanguay RL Workflow for Comparison of Chemical and Biological Metrics of Filter Collected PM(2.5). Atmos Environ (1994) PubMed PMC7170255

2019

Shankar P, Geier MC, Truong L, Mcclure RS, Pande P, Waters KM, Tanguay RL Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard. Int J Mol Sci PubMed PMC6566387

Brown JM, Phillips AR, Lewis DA, Mans M, Chang Y, Tanguay RL, Peterson ES, Waters KM, Tilton SC Bioinformatics Resource Manager: a systems biology web tool for microRNA and omics data integration. BMC Bioinformatics PubMed PMC6525352

Trine LS, Davis EL, Roper C, Truong L, Tanguay RL, Simonich SL Formation of PAH Derivatives and Increased Developmental Toxicity during Steam Enhanced Extraction Remediation of Creosote Contaminated Superfund Soil. Environ Sci Technol PubMed PMC7103206

Thomas DG, Shankaran H, Truong L, Tanguay RL, Waters KM Time-dependent behavioral data from zebrafish reveals novel signatures of chemical toxicity using point of departure analysis. Comput Toxicol PubMed PMC6726397

Roper C, Trine LS, Barrett D, Simonich SL, Tanguay RL PM(2.5) Filter Extraction Methods: Implications for Chemical and Toxicological Analyses. Environ Sci Technol PubMed PMC6652177

Hagstrom D, Truong L, Zhang S, Tanguay RL, Collins ES Comparative Analysis of Zebrafish and Planarian Model Systems for Developmental Neurotoxicity Screens Using an 87-Compound Library. Toxicol Sci PubMed PMC6317421

2018

Garcia GR, Shankar P, Dunham CL, Garcia A, Ladu JK, Truong L, Tilton SC, Tanguay RL Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA (slincR) Using the Zebrafish Model. Environ Health Perspect PubMed PMC6371766

Geier MC, Minick DJ, Truong L, Tilton SC, Pande P, Anderson KA, Teeguarden JG, Tanguay RL Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish. Toxicol Appl Pharmacol PubMed PMC6087484

Balik-meisner M, Truong L, Scholl EH, Ladu JK, Tanguay RL, Reif DM Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure. Environ Health Perspect PubMed PMC6084885

Roper C, Simonich SL, Tanguay RL Development of a high-throughput in vivo screening platform for particulate matter exposures. Environ Pollut PubMed PMC5951187

Bugel SM, Tanguay RL Multidimensional chemobehavior analysis of flavonoids and neuroactive compounds in zebrafish. Toxicol Appl Pharmacol PubMed PMC5912343

Haggard DE, Noyes PD, Waters KM, Tanguay RL Transcriptomic and phenotypic profiling in developing zebrafish exposed to thyroid hormone receptor agonists. Reprod Toxicol PubMed PMC5878140

Geier MC, Chlebowski AC, Truong L, Simonich SL, Anderson KA, Tanguay RL Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons. Arch Toxicol PubMed PMC5820187

Balik-meisner M, Truong L, Scholl EH, Tanguay RL, Reif DM Population genetic diversity in zebrafish lines. Mamm Genome PubMed PMC5851690

2017

Bergmann AJ, Tanguay RL, Anderson KA Using passive sampling and zebrafish to identify developmental toxicants in complex mixtures. Environ Toxicol Chem PubMed

Knecht AL, Truong L, Marvel SW, Reif DM, Garcia A, Lu C, Simonich MT, Teeguarden JG, Tanguay RL Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish. Toxicol Appl Pharmacol PubMed PMC5539966

Schrlau JE, Kramer AL, Chlebowski AC, Truong L, Tanguay RL, Simonich SL, Semprini L Formation of Developmentally Toxic Phenanthrene Metabolite Mixtures by Mycobacterium sp. ELW1. Environ Sci Technol PubMed PMC5996983

Garcia GR, Goodale BC, Wiley MW, Ladu JK, Hendrix DA, Tanguay RL In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression. Mol Pharmacol PubMed PMC5438132

Chlebowski AC, Garcia GR, Ladu JK, Bisson WH, Truong L, Simonich SL, Tanguay RL Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs. Toxicol Sci PubMed PMC5414855

Haggard DE, Das SR, Tanguay RL Comparative Toxicogenomic Responses to the Flame Retardant mITP in Developing Zebrafish. Chem Res Toxicol PubMed

Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades. Toxicol Appl Pharmacol PubMed PMC5224523

Knecht AL, Truong L, Simonich MT, Tanguay RL Developmental benzo[a]pyrene (B[a]P) exposure impacts larval behavior and impairs adult learning in zebrafish. Neurotoxicol Teratol PubMed PMC5235990

2016

Noyes PD, Garcia GR, Tanguay RL ZEBRAFISH AS AN IN VIVO MODEL FOR SUSTAINABLE CHEMICAL DESIGN. Green Chem PubMed PMC5408959

Olivares CI, Sierra-alvarez R, Abrell L, Chorover J, Simonich MT, Tanguay RL, Field JA Zebrafish embryo toxicity of anaerobic biotransformation products from the insensitive munitions compound 2,4-dinitroanisole. Environ Toxicol Chem PubMed PMC5052101

Bugel SM, Bonventre JA, Tanguay RL Comparative Developmental Toxicity of Flavonoids Using an Integrative Zebrafish System. Toxicol Sci PubMed PMC5091365

Haggard DE, Noyes PD, Waters KM, Tanguay RL Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish. Toxicol Appl Pharmacol PubMed PMC5023494

Truong L, Bugel SM, Chlebowski AC, Usenko CY, Simonich MT, Simonich SL, Tanguay RL Optimizing multi-dimensional high throughput screening using zebrafish. Reprod Toxicol PubMed PMC5067206

Teeguarden JG, Tan Y, Edwards SW, Leonard JA, Anderson KA, Corley RA, Kile ML, Simonich SL, Stone DL, Tanguay RL, Waters KM, Harper SL, Williams DE Expanding on Successful Concepts, Models, and Organization. Environ Sci Technol PubMed

Chlebowski AC, Tanguay RL, Simonich SL Quantitation and prediction of sorptive losses during toxicity testing of polycyclic aromatic hydrocarbon (PAH) and nitrated PAH (NPAH) using polystyrene 96-well plates. Neurotoxicol Teratol PubMed PMC5454028

Zhang G, Marvel S, Truong L, Tanguay RL, Reif DM Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure. Reprod Toxicol PubMed PMC4905797

Reif DM, Truong L, Mandrell D, Marvel S, Zhang G, Tanguay RL High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes. Arch Toxicol PubMed PMC4701642

Teeguarden JG, Tan Y, Edwards SW, Leonard JA, Anderson KA, Corley RA, Kile ML, Simonich SL, Stone DL, Tanguay RL, Waters KM, Harper SL, Williams DE Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework. Environ Sci Technol PubMed PMC4854780

Garcia GR, Noyes PD, Tanguay RL Advancements in zebrafish applications for 21st century toxicology. Pharmacol Ther PubMed PMC4851906

Bugel SM, Wehmas LC, Ladu JK, Tanguay RL Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium. Toxicol Appl Pharmacol PubMed PMC4792761

Olivares CI, Field JA, Simonich MT, Tanguay RL, Sierra-alvarez R Arsenic (III, V), indium (III), and gallium (III) toxicity to zebrafish embryos using a high-throughput multi-endpoint in vivo developmental and behavioral assay. Chemosphere PubMed PMC4754138

2015

Chibwe L, Geier MC, Nakamura J, Tanguay RL, Aitken MD, Simonich SL Aerobic Bioremediation of PAH Contaminated Soil Results in Increased Genotoxicity and Developmental Toxicity. Environ Sci Technol PubMed PMC4666737

Goodale BC, La Du JK, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs. Toxicol Sci PubMed PMC4612346

Elie MR, Choi J, Nkrumah-elie YM, Gonnerman GD, Stevens JF, Tanguay RL Metabolomic analysis to define and compare the effects of PAHs and oxygenated PAHs in developing zebrafish. Environ Res PubMed PMC4492807

Chatterjee P, Padmanarayana M, Abdullah N, Holman CL, Ladu JK, Tanguay RL, Johnson CP Otoferlin deficiency in zebrafish results in defects in balance and hearing: rescue of the balance and hearing phenotype with full-length and truncated forms of mouse otoferlin. Mol Cell Biol PubMed PMC4333087

2014

Perkins A, Phillips J, Kerkvliet NI, Tanguay RL, Perdew G, Kolluri SK, Bisson WH A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain. Biology (Basel) PubMed PMC4280506

Gerlach CV, Das SR, Volz DC, Bisson WH, Kolluri SK, Tanguay RL Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish. Aquat Toxicol PubMed PMC4090055

Truong L, Mandrell D, Mandrell R, Simonich MT, Tanguay RL A rapid throughput approach identifies cognitive deficits in adult zebrafish from developmental exposure to polybrominated flame retardants. Neurotoxicology PubMed PMC4134748

Bugel SM, Bonventre JA, White LA, Tanguay RL, Cooper KR Chronic exposure of killifish to a highly polluted environment desensitizes estrogen-responsive reproductive and biomarker genes. Aquat Toxicol PubMed PMC4084733

Chen J, Tanguay RL, Tal TL, Gai Z, Ma X, Bai C, Tilton SC, Jin D, Yang D, Huang C, Dong Q Early life perfluorooctanesulphonic acid (PFOS) exposure impairs zebrafish organogenesis. Aquat Toxicol PubMed PMC4159678

Truong L, Reif DM, Mary LS, Geier MC, Truong HD, Tanguay RL Multidimensional in vivo hazard assessment using zebrafish. Toxicol Sci PubMed PMC3871932

2013

Franzosa JA, Bugel SM, Tal TL, Ladu JK, Tilton SC, Waters KM, Tanguay RL Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects. FASEB J PubMed PMC3834785

Goodale BC, Tilton SC, Corvi MM, Wilson GR, Janszen DB, Anderson KA, Waters KM, Tanguay RL Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish. Toxicol Appl Pharmacol PubMed PMC4098828

Knecht AL, Goodale BC, Truong L, Simonich MT, Swanson AJ, Matzke MM, Anderson KA, Waters KM, Tanguay RL Comparative developmental toxicity of environmentally relevant oxygenated PAHs. Toxicol Appl Pharmacol PubMed PMC3976560

Truong L, Denardo MA, Kundu S, Collins TJ, Tanguay RL Zebrafish Assays as Developmental Toxicity Indicators in The Design of TAML Oxidation Catalysts. Green Chem PubMed PMC3989102

Saili KS, Tilton SC, Waters KM, Tanguay RL Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17β-estradiol in embryonic zebrafish. Reprod Toxicol PubMed PMC3690774

Truong L, Tilton SC, Zaikova T, Richman E, Waters KM, Hutchison JE, Tanguay RL Surface functionalities of gold nanoparticles impact embryonic gene expression responses. Nanotoxicology PubMed PMC3399027

Adenuga AA, Truong L, Tanguay RL, Remcho VT Preparation of water soluble carbon nanotubes and assessment of their biological activity in embryonic zebrafish. Int J Biomed Nanosci Nanotechnol PubMed PMC4349379

2012

Chen J, Huang C, Truong L, Ladu JK, Tilton SC, Waters KM, Lin K, Tanguay RL, Dong Q Early life stage trimethyltin exposure induces ADP-ribosylation factor expression and perturbs the vascular system in zebrafish. Toxicology PubMed PMC3511642

Allan SE, Smith BW, Tanguay RL, Anderson KA Bridging environmental mixtures and toxic effects. Environ Toxicol Chem PubMed PMC3502726

Tilton SC, Tal TL, Scroggins SM, Franzosa JA, Peterson ES, Tanguay RL, Waters KM Bioinformatics Resource Manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools. BMC Bioinformatics PubMed PMC3534564

Tal TL, Tanguay RL Non-coding RNAs--novel targets in neurotoxicity. Neurotoxicology PubMed PMC3462486

Tal TL, Franzosa JA, Tilton SC, Philbrick KA, Iwaniec UT, Turner RT, Waters KM, Tanguay RL MicroRNAs control neurobehavioral development and function in zebrafish. FASEB J PubMed PMC3316906

Mandrell D, Truong L, Jephson C, Sarker MR, Moore A, Lang C, Simonich MT, Tanguay RL Automated zebrafish chorion removal and single embryo placement: optimizing throughput of zebrafish developmental toxicity screens. J Lab Autom PubMed PMC3327291

Saili KS, Corvi MM, Weber DN, Patel AU, Das SR, Przybyla J, Anderson KA, Tanguay RL Neurodevelopmental low-dose bisphenol A exposure leads to early life-stage hyperactivity and learning deficits in adult zebrafish. Toxicology PubMed PMC3245816

Fieber LA, Tanguay RL, Walter RB, Williams DE Aquatic animal models of human disease: selected papers from the 5th conference. Comp Biochem Physiol C Toxicol Pharmacol PubMed

2010

O'donnell EF, Saili KS, Koch DC, Kopparapu PR, Farrer D, Bisson WH, Mathew LK, Sengupta S, Kerkvliet NI, Tanguay RL, Kolluri SK The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor. PLoS One PubMed PMC2948512

Hillwalker WE, Allan SE, Tanguay RL, Anderson KA Exploiting lipid-free tubing passive samplers and embryonic zebrafish to link site specific contaminant mixtures to biological responses. Chemosphere PubMed PMC2833334

Li J, Shang X, Zhao Z, Tanguay RL, Dong Q, Huang C Polycyclic aromatic hydrocarbons in water, sediment, soil, and plants of the Aojiang River waterway in Wenzhou, China. J Hazard Mater PubMed PMC3270495

2009

Bisson WH, Koch DC, O'donnell EF, Khalil SM, Kerkvliet NI, Tanguay RL, Abagyan R, Kolluri SK Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands. J Med Chem PubMed PMC3289977

1905

Rericha Y, Mary LS, Truong L, Mcclure RS, Martin JK, Leonard SW, Thunga P, Simonich MT, Waters KM, Field JA, Tanguay RL Diverse PFAS produce unique transcriptomic changes linked to developmental toxicity in zebrafish. Front Toxicol PubMed PMC11298493

Dasgupta S, Simonich MT, Tanguay RL Developmental Toxicity Assessment Using Zebrafish-Based High-Throughput Screening. Methods Mol Biol PubMed

Mcclure RS, Rericha Y, Waters KM, Tanguay RL 3' RNA-seq is superior to standard RNA-seq in cases of sparse data but inferior at identifying toxicity pathways in a model organism. Front Bioinform PubMed PMC10414111

Wilson LB, Mcclure RS, Waters KM, Simonich MT, Tanguay RL Concentration-response gene expression analysis in zebrafish reveals phenotypically-anchored transcriptional responses to retene. Front Toxicol PubMed PMC9453431

Wallis DJ, Ladu JK, Thunga P, Elson DJ, Truong L, Kolluri SK, Tanguay RL, Reif DM Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model. Front Toxicol PubMed PMC9098949

Thunga P, Truong L, Tanguay RL, Reif DM Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification. Front Toxicol PubMed PMC8915815

Dasgupta S, Dunham CL, Truong L, Simonich MT, Sullivan CM, Tanguay RL Phenotypically Anchored mRNA and miRNA Expression Profiling in Zebrafish Reveals Flame Retardant Chemical Toxicity Networks. Front Cell Dev Biol PubMed PMC8063052

Garcia GR, Bugel SM, Truong L, Spagnoli S, Tanguay RL AHR2 required for normal behavioral responses and proper development of the skeletal and reproductive systems in zebrafish. PLoS One PubMed PMC5832240

Chlebowski AC, Ladu JK, Truong L, Simonich SL, Tanguay RL Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing. Toxicol Rep PubMed PMC5527975

Zhang G, Truong L, Tanguay RL, Reif DM A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish. PLoS One PubMed PMC5242475

Titaley IA, Chlebowski AC, Truong L, Tanguay RL, Simonich SL Identification and Toxicological Evaluation of Unsubstituted PAHs and Novel PAH Derivatives in Pavement Sealcoat Products. Environ Sci Technol Lett PubMed PMC6075666

Truong L, Simonich MT, Tanguay RL Better, Faster, Cheaper: Getting the Most Out of High-Throughput Screening with Zebrafish. Methods Mol Biol PubMed

Weber DN, Hoffmann RG, Hoke ES, Tanguay RL Bisphenol A exposure during early development induces sex-specific changes in adult zebrafish social interactions. J Toxicol Environ Health A PubMed PMC4246420

Goodale BC, Ladu JK, Bisson WH, Janszen DB, Waters KM, Tanguay RL AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish. PLoS One PubMed PMC3252317