• Friday, June 7, 2024

    1:00-2:00 PM
    Location: Hallie Ford rm 115


    Emily Ho and Diana Rohlman (TRSC & CEC)

    Dr. Emily Ho's research interests are in the area of antioxidants and gene expression and dietary chemoprevention strategies. She is the leader of the EHSC Translational Research Support Core, Directory of the Linus Pauling Institute, and Co-Director of the Center for Healthy Aging Research.

    Dr. Diana Rohlman studies the role of environmental health literacy in helping communities better frame and respond to environmental health hazards. She is the leader of the EHSC Community Engagement Core and co-leader of the SRC Community Engagment Core, where she is working to bring researchers and impacted communities together on collaborative projects.

  • Friday, May 3, 2024

    11:00-12:00 PM (PST)
    Location: Agricultural & Life Sciences, room 4000
    Serhan Mermer

    Understanding the National Pesticide Information Center; who we are and what we do?

    Serhan Mermer
    Director of National Pesticide Information Center
    Assistant Professor, Oregon State University

    NPIC provides objective, science-based information about pesticides and pesticide-related topics to enable people to make informed decisions about pesticides and their use. NPIC is a cooperative agreement between Oregon State University and the U.S. Environmental Protection Agency. 

  • Friday, December 8, 2023

    11:00AM-12:00 PM
    Location: ALS 4001 (email shawn . tucker @ oregonstate . edu for zoom info)

    Parichehr Salimifard

    Culbertson Faculty Scholar
    Assistant Professor, Civil and Construction Engineering
    Oregon State University

    Buildings have far-reaching impacts on public health and well-being. Buildings are the largest energy use sector and they have had the least improvement in their energy efficiency compared to other sectors. Therefore, they are responsible for the majority of the emissions, and at the same time, they also present a great opportunity in reducing energy consumption and emissions by making buildings more energy efficient. Buildings are also where people spend about 90% of their lifetime.
    The indoor environment affects people’s health and well-being, performance, and productivity. Therefore, it is critical to have buildings that are high-performing and also healthy and resilient.
    In this presentation, Dr. Salimifard will share her academic career journey as well as some of her research projects focusing on the connections between indoor air quality, building energy performance, emissions footprint of buildings and their climate impacts, and public health impacts of buildings, and how to leverage building science to design and operate buildings that are sustainable, healthy, and resilient.

  • Friday, October 6, 2023

    11:00AM-12:00 PM
    Location: TBD (email shawn . tucker @ oregonstate . edu for zoom info)

    Adverse Outcome Pathways For Thyroid Disruption: Filling The Gaps From In Vitro Screens To Developmental Neurotoxicity In A Mammalian System

    Mary Gilbert
    Senior Investigator
    United States Environmental Protection Agency | US EPA · Center for Public Health and Environmental Assessment

    The complexity of the thyroid hormone signaling pathways present a myriad of targets for interference by environmental chemicals.  Because thyroid hormones are essential for normal brain development, there is a significant public health need to protect the developing brain of the fetus, newborn, and young child from thyroid system-disrupting chemicals (TSDC). This concern has led to the development of a suite of in vitro-based methodologies (NAMs) targeting specific sites within the thyroid system where chemicals may act.  Currently, regulatory decisions for TSDC are largely based on alterations in circulating levels of thyroid hormone in rodent studies, but translation from NAM outputs to serum hormones is lacking. So too is our understanding of the relationships between concentrations of TH in serum, target tissues, and the downstream effects on brain development. This presentation will provide an overview of current approaches to identify and characterize TSDCs for informed regulatory decision making. It will focus ongoing research efforts to unravel how TSDC interfere with thyroid signaling at the molecular, structural, and functional level using a case study with the drinking water contaminant perchlorate.  Does not reflect US EPA policy. 

  • Friday, August 4, 2023

    11:00 AM-12:00 PM
    Location: ALS 4001 and Zoom (email shawn tucker for info)

    Microbes, Methods, And Remediation: A Journey To Novel Pah Bioremediation Strategies

    Juliana Huizenga
    PhD Candidate
    Oregon State University Environmental Engineering

    Polycyclic aromatic hydrocarbons (PAHs) are a class of environmental contaminants associated with carcinogenic, mutagenic, and teratogenic health effects. Bioremediation is an attractive option for PAH remediation due to its low cost and low energy requirements, however bioremediation can lead to the formation of toxic PAH transformation products. In pursuit of novel bioremediation strategies, exploratory work was conducted with the pure bacterial culture Rhodococcus rhodochrous ATCC 21198 and monoaromatic hydrocarbons (BTEX), which provided the foundation for PAH bioremediation strategies. PAH bioremediation studies required monitoring methods that could provide results in real-time, which traditional analytical techniques could not provide. Thus, a method for rapid analysis of PAHs in aqueous samples was developed using excitation-emission matrix (EEM) fluorescent spectroscopy and parallel factor analysis (PARAFAC) that eliminated the need for extensive sample preparation and separation techniques before analysis. This work also inspired additional method development endeavors for a more complex biological system: embryonic zebrafish. Following the foundational microbial work and method development research phases, our work in PAH remediation technologies has commenced and expanded to include surfactants and immobilized cells for combined remediation strategies. Metrics for remediation success included reduction of parent PAH concentrations, accumulation of PAH metabolites, and overall toxicity of the treated material. Outcomes of this research has demonstrated the utility of 21198 as a candidate for aromatic hydrocarbon bioremediation, provided a new tool for monitoring aqueous PAH concentrations in biological systems, and highlighted the importance of toxicity considerations in PAH remediation efforts. 

  • Friday, July 14, 2023

    11:00AM-12:00 PM
    Location: TBD

    Writing Data Management Plans

    Clara Llebot
    Oregon State University
  • Friday, June 2, 2023

    11:00AM-12:00 PM
    Location: TBD (email shawn . tucker @ oregonstate . edu for zoom info)

    Identification of physiologic and dietary Ah receptor ligands key to understanding function

    Gary Perdew
    H. Thomas and Dorothy Willits Hallowell Chair in Agricultural Sciences
    Penn State
  • Friday, April 7, 2023

    12:00-1:00 PM
    Location: TBD

    A Fraction-Based Approach to Mixture Risk Evaluation: PPRTV Assessment for Complex Mixtures of Aliphatic and Aromatic Hydrocarbons

    Allison Phillips
    US Environmental Protection Agency (EPA)

    Total petroleum hydrocarbon (TPH) contamination is present at numerous Superfund sites across the nation. Hydrocarbon products are complex mixtures containing perhaps hundreds of hydrocarbon compounds and compositions vary among different products. Once released, the composition of a hydrocarbon product will change due to differential fate and transport of its components. To estimate the human health hazards and risk associated with TPH exposure at Superfund sites, a fraction-based approach was taken in the Provisional Peer Reviewed Toxicity Value (PPRTV) assessment of these complex mixtures. The TPH mixture was divided into 6 subfractions, defined based on structural attributes and further categorized by carbon and equivalent carbon ranges. The health risk of each fraction can be estimated using a variety mixture assessment approaches, including the indicator chemical method, surrogate mixture method, hazard index method, or relative potency factor method, with method selection driven by data availability. Fraction-specific hazard and risk estimates are then summed using either dose (noncancer) or response (cancer) addition to provide an estimate of mixture hazard or risk. Background on the PPRTV Program, mixture risk assessment methods, and an example calculation will be presented.

  • Friday, March 3, 2023

    11:00AM-12:00 PM
    Location: Linus Pauling Science Center, Room 402 and Zoom (Email Shawn Tucker for zoom info)

    2023 PNW-CTEHR Pilot Project Ignite Pitch Talks

    Pacific Northwest Center for Translational Environmental Health Research

    Applicants for the Pacific Northwest Center for Translational Environmental Health
    Pilot Project Program will be sharing their research ideas in short Ignite Pitches.
    This is a chance to learn about the state-of-the-art science, technology, and
    stakeholder engagement ideas being pursued by members in the Center and ask questions about their latest
    research ideas.

    Speakers: Each speaker has 6 minutes to share their ideas followed by 4 minutes for questions.

    The Oregon Human Microplastics Project: assessing microplastics exposure via intake and microbiome survey to identify potential impacts on health

    Susan Brander

    New Determinants of TCDD Signaling

    Siva Kolluri

    Cometabolic Treatment of 1,2,3-Trichloropropane in Hydrogel Beads and the Evaluation of Toxicity Reduction Using Embryonic Zebrafish Assays

    Lew Semprini

    Non-calcemic vitamin D-hydroxyderivative 20(OH)D3 as preventive agent against UV induced DNA damage and spontaneous melanoma

    Arup Indra

    Neurotoxic Signatures of Drinking Water Contaminants

    Manuel Garcia-Jaramillo
  • Friday, February 3, 2023

    12:00-1:00 PM
    Location: TBD

    Stephania Cormier

    Respiratory Immunology
    Louisiana State University A&M Medical Center