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The Sinnhuber Aquatic Research Laboratory (SARL) is the world’s largest zebrafish aquatic toxicology facility. This laboratory is a unique facility equipped to conduct biomedical research using zebrafish. It is a 17,000 square foot self-contained fish hatchery for rearing fish. It remains the only known certified SPF zebrafish facility and has a low maintenance system with >40,000 fish and >20 transgenic zebrafish lines. Animals spawn daily, producing tens of thousands of high-quality eggs/day. The facility also supports transgenic studies, CRISPR/Cas9 line development, morpholino injections, dietary studies and is equipped for chemical assessments.
SARL is an off-campus research facility located 2.9 miles from Oregon State University.
Oregon State University is AAALAC accredited. All animals are under approved Animal Care and Use Protocols as required by the institutional IACUC. Animals are housed at the SARL in commercial holding rack units to house adult and larval fish. SARL is home to one of the largest zebrafish toxicology research facilities globally and the only one in the world that is Specific Pathogen Free for Pseudoloma neurophilia, providing confidence in the health of the animals used in these studies. Current animal capacity consists of over 4,000 X 1-6 liter tanks. In addition, we have developed novel 100 and 35-gallon mass egg production tanks. These tanks result in significantly reduced labor costs and unprecedented capacity to produce zebrafish eggs daily. Average daily production exceeds 40,000 eggs. We have developed and obtained several transgenic and mutant zebrafish lines that are available for research. Finally, we also have in-house capabilities to generate mutant fish using zinc finger nucleases, TALENs, and CRISPR Cas-9 methods
Take a tour of the fish room by clicking anywhere on the screen. Hold and drag your cursor to look around the space and click on the arrows to move through the rooms. Click on the + symbol to see more photographs, watch short videos, or listen to brief audio clips.
Take a tour of the lab by clicking anywhere on the screen. Hold and drag your cursor to look around the space and click on the arrows to move through the rooms. Click on the + symbol to see more photographs, watch short videos, or listen to brief audio clips.
SARL is a state of the art research facility with numerous capabilities that are available to the scientific community. We provide services from distributing zebrafish, zebrafish husbandry to molecular techniques. Below is a list of some of the capabilities: